منابع مشابه
Azathioprine shock.
Azathioprine has been used as an immunosuppressant for over 20 years in cancer chemotherapy, organ transplantation and diseases with confirmed or suspected immune mechanisms. A hypersensitivity reaction manifesting as fever, rash, myalgia and a neutrophil leucocytosis occurring about 2 weeks after exposure is well documented and has been confirmed by challenge testing. Hypotensive reactions are...
متن کاملCorticosteroids – Azathioprine
Fifteen years ago, classical immunosuppressive therapy was inconceivable without corticosteroids and azathioprine. A large number of transplantees administering these drugs had successful immunosuppression and good function of the graft over longer period of time. Nevertheless, side-effects of corticosteroids to cardiovascular system (hypertension, congestive heart failure, thrombophlebitis), t...
متن کاملAzathioprine in dermatology.
Azathioprine is a synthetic purine analog derived from 6-mercaptopurine. It is a purine antagonist and its active metabolites act by disrupting the function of endogenous purines. It has a cytotoxic and immunosuppressive mechanism of action. It is used in dermatology for treatment of immunobullous diseases, generalized eczematous disorders and photodermatoses. There is an enzyme in the metaboli...
متن کاملAzathioprine-induced shock.
sufflation in peripheral vascular disease. The gas, from 100 to 400 ml, is injected directly via an arterial catheter, the site depending on the angiographically demonstrated arterial supply to the limb. I have reserved the method mainly for those who are not suitable for angioplasty and in whom surgery is not contemplated. Twenty-one such patients, with generally severe and widespread disease,...
متن کاملazathioprine. A pilot study
Objective-To study the possible association of purine enzyme activities with response to azathioprine (AZA) treatment in rheumatoid arthritis (RA) and their correlation with parameters of disease activity. Patients and methods--Lymphocyte activities of hypoxanthine-guanine phosphoribosyl-transferase (HGPRT), adenine phosphoribosyltransferase (APRT), purine nucleoside phosphorylase (PNP) and 5'-...
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ژورنال
عنوان ژورنال: Reactions Weekly
سال: 2021
ISSN: ['1179-2051', '0114-9954']
DOI: https://doi.org/10.1007/s40278-021-94946-4